10 Largest pharmacies in the United States in 2025

Last updated on March 04, 2025

What is the largest pharmacy in the United States?

Express Scripts is the largest pharmacy the United States in 2025.
Express Scripts

45,948

LOCATIONS

EXPRESS SCRIPTS

Largest pharmacy in 47 out of 56 States and Territories


CVS Pharmacy

9,118

LOCATIONS

CVS PHARMACY

Largest pharmacy in 4 out of 56 States and Territories


Walgreens

8,404

LOCATIONS

WALGREENS

Largest pharmacy in 2 out of 56 States and Territories


What are the largest pharmacies in the United States in 2025?

Express Scripts, CVS Pharmacy and Walgreens are the largest pharmacies in the United States in 2025 based on the number of locations. Express Scripts has the most number of locations with 45,948 locations across 52 states and territories. CVS Pharmacy has 9,118 and Walgreens has 8,404 locations in the US. These three together make 85.67% of the largest 10 pharmacies in the US.

Rank Brand Number of Locations States Present In Cities Present In Download Dataset
#1
Express Scripts
Express Scripts 45,948 52 6,544
#2
CVS Pharmacy
CVS Pharmacy 9,118 51 3,455
#3
Walgreens
Walgreens 8,404 53 3,400
#4
Health Mart
Health Mart 4,422 52 2,302
#5
Good Neighbor Pharmacy
Good Neighbor Pharmacy 2,418 53 1,621
#6
Rite Aid
Rite Aid 1,258 15 842
#7
Genoa Healthcare
Genoa Healthcare 766 48 555
#8
Safeway Pharmacy
Safeway Pharmacy 752 18 456
#9
The Vitamin Shoppe
The Vitamin Shoppe 689 46 561
#10
Albertsons Pharmacy
Albertsons Pharmacy 312 15 191


Learn more about 10 Largest pharmacies in the United States in 2025

Express Scripts

There are 45,948 Express Scripts pharmacies in the United States as of August 17, 2023. The state and territory with the most number of Express Scripts locations in the US is California, with 4,879 pharmacies, which is about 11% of all Express Scripts pharmacies in the US.

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CVS Pharmacy

There are 9,118 CVS Pharmacy locations in the United States as of March 17, 2025. The state and territory with the most number of CVS Pharmacy locations in the US is California, with 1,072 locations, which is about 12% of all CVS Pharmacy locations in the US.

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Walgreens

There are 8,363 Walgreens pharmacies in the United States as of March 15, 2025. The state and territory with the most number of Walgreens locations in the US is Florida, with 797 pharmacies, which is about 10% of all Walgreens pharmacies in the US.

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Health Mart

There are 4,422 Health Mart pharmacies in the United States as of March 04, 2025. The state and territory with the most number of Health Mart locations in the US is California, with 495 pharmacies, which is about 11% of all Health Mart pharmacies in the US.

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Good Neighbor Pharmacy

There are 2,418 Good Neighbor Pharmacy locations in the United States as of February 18, 2025. The state and territory with the most number of Good Neighbor Pharmacy locations in the US is California, with 272 locations, which is about 11% of all Good Neighbor Pharmacy locations in the US.

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Rite Aid

There are 1,250 Rite Aid pharmacies in the United States as of March 18, 2025. The state and territory with the most number of Rite Aid locations in the US is Pennsylvania, with 349 pharmacies, which is about 28% of all Rite Aid pharmacies in the US.

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Genoa Healthcare

There are 766 Genoa Healthcare locations in the United States as of July 26, 2024. The state and territory with the most number of Genoa Healthcare locations in the US is Arizona, with 66 locations, which is about 9% of all Genoa Healthcare locations in the US.

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Safeway Pharmacy

There are 752 Safeway Pharmacy locations in the United States as of January 15, 2025. The state and territory with the most number of Safeway Pharmacy locations in the US is Washington, with 163 locations, which is about 22% of all Safeway Pharmacy locations in the US.

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The Vitamin Shoppe

There are 689 The Vitamin Shoppe stores in the United States as of February 18, 2025. The state and territory with the most number of The Vitamin Shoppe locations in the US is Florida, with 80 stores, which is about 12% of all The Vitamin Shoppe stores in the US.

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Albertsons Pharmacy

There are 312 Albertsons Pharmacy locations in the United States as of January 15, 2025. The state and territory with the most number of Albertsons Pharmacy locations in the US is California, with 87 locations, which is about 28% of all Albertsons Pharmacy locations in the US.

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