What is the largest pharmacy in the United States?
Express Scripts is the largest pharmacy the United States in 2025.What are the largest pharmacies in the United States in 2025?
Express Scripts, CVS Pharmacy and Walgreens are the largest pharmacies in the United States in 2025 based on the number of locations. Express Scripts has the most number of locations with 45,948 locations across 52 states and territories. CVS Pharmacy has 9,118 and Walgreens has 8,404 locations in the US. These three together make 85.67% of the largest 10 pharmacies in the US.
Rank | Brand | Number of Locations | States Present In | Cities Present In | Download Dataset | |
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#1 |
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Express Scripts | 45,948 | 52 | 6,544 | |
#2 |
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CVS Pharmacy | 9,118 | 51 | 3,455 | |
#3 |
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Walgreens | 8,404 | 53 | 3,400 | |
#4 |
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Health Mart | 4,422 | 52 | 2,302 | |
#5 |
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Good Neighbor Pharmacy | 2,418 | 53 | 1,621 | |
#6 |
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Rite Aid | 1,258 | 15 | 842 | |
#7 |
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Genoa Healthcare | 766 | 48 | 555 | |
#8 |
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Safeway Pharmacy | 752 | 18 | 456 | |
#9 |
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The Vitamin Shoppe | 689 | 46 | 561 | |
#10 |
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Albertsons Pharmacy | 312 | 15 | 191 |
Learn more about 10 Largest pharmacies in the United States in 2025

Express Scripts
There are 45,948 Express Scripts pharmacies in the United States as of August 17, 2023. The state and territory with the most number of Express Scripts locations in the US is California, with 4,879 pharmacies, which is about 11% of all Express Scripts pharmacies in the US.
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CVS Pharmacy
There are 9,118 CVS Pharmacy locations in the United States as of March 17, 2025. The state and territory with the most number of CVS Pharmacy locations in the US is California, with 1,072 locations, which is about 12% of all CVS Pharmacy locations in the US.
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Walgreens
There are 8,363 Walgreens pharmacies in the United States as of March 15, 2025. The state and territory with the most number of Walgreens locations in the US is Florida, with 797 pharmacies, which is about 10% of all Walgreens pharmacies in the US.
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Health Mart
There are 4,422 Health Mart pharmacies in the United States as of March 04, 2025. The state and territory with the most number of Health Mart locations in the US is California, with 495 pharmacies, which is about 11% of all Health Mart pharmacies in the US.
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Good Neighbor Pharmacy
There are 2,418 Good Neighbor Pharmacy locations in the United States as of February 18, 2025. The state and territory with the most number of Good Neighbor Pharmacy locations in the US is California, with 272 locations, which is about 11% of all Good Neighbor Pharmacy locations in the US.
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Rite Aid
There are 1,250 Rite Aid pharmacies in the United States as of March 18, 2025. The state and territory with the most number of Rite Aid locations in the US is Pennsylvania, with 349 pharmacies, which is about 28% of all Rite Aid pharmacies in the US.
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Genoa Healthcare
There are 766 Genoa Healthcare locations in the United States as of July 26, 2024. The state and territory with the most number of Genoa Healthcare locations in the US is Arizona, with 66 locations, which is about 9% of all Genoa Healthcare locations in the US.
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Safeway Pharmacy
There are 752 Safeway Pharmacy locations in the United States as of January 15, 2025. The state and territory with the most number of Safeway Pharmacy locations in the US is Washington, with 163 locations, which is about 22% of all Safeway Pharmacy locations in the US.
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The Vitamin Shoppe
There are 689 The Vitamin Shoppe stores in the United States as of February 18, 2025. The state and territory with the most number of The Vitamin Shoppe locations in the US is Florida, with 80 stores, which is about 12% of all The Vitamin Shoppe stores in the US.
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Albertsons Pharmacy
There are 312 Albertsons Pharmacy locations in the United States as of January 15, 2025. The state and territory with the most number of Albertsons Pharmacy locations in the US is California, with 87 locations, which is about 28% of all Albertsons Pharmacy locations in the US.
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